Dating results reflect the estimated age of the alternate allele. For the latter, results from the pairwise inference of TMRCA between haplotype pairs independently in each data set were combined to re-estimate allele age.
All concordant pairs were sampled at random from the set of possible concordant pairs for a given variant. Discordant pairs were sampled after applying a "relaxed" prioritisation algorithm to identify non-carrier haplotypes that are the nearest genealogical datings site to the focal sub-tree carriers.
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